SteriGene

At the heart of the all-new SteriGENE formula are the micro-emulsion particles (Nano particles) that enable the active ingredient molecules in the product to be carried rapidly through cell walls of micro-organisms.

Rapid penetration of cell walls by the powerful SteriGENE disinfectant constituents ensures cell death is equally rapid. SteriGENE works up to 70% quicker than conventional high level disinfectants and achieves apoptosis (cell death) rather than merely suspending activity as with conventional disinfectant products.

Because the Nano Particles can enter areas like microscopic fissures and crevices in hard surfaces, which have not hitherto been penetrable by conventional carrier systems, disinfectant actives are able to spread across a complete surface area, to perform a far more thorough anti pathogenic cleansing task than was previously possible.

The synergistic blend of SteriGENE active ingredients produces the fastest acting and most efficient anti viral and sporicidal agent presently available in non-oxidising disinfectant technology.

Health and safety issues and product compatibility are of real importance to everyone.

EA International encourages all users of chemical products to pay special attention to the advisory statements within Material Safety Data Sheets and on product labelling.

SteriGENE is able to rely on lower levels of active ingredients than previously used, due to the formulation’s revolutionary method of delivering diluted disinfectant to the cells of micro-organisms. The simple prokaryotic cellular structure of micro-organisms provides little resistance to the active ingredients of SteriGENE but the hugely more complex eukaryotic structure of the mammalian cell membrane means SteriGENE is not cyto-toxic to mammalian tissue. Using the new system in the presence of human and animal skin is therefore of low risk. Notwithstanding this, instructions should always be followed carefully and gloves worn where advised.

Independent laboratory testing demonstrates no corrosion or deterioration of the following materials, even after long-term repeated immersions: Rubber compounds, Plastics, Fibreglass, Stainless Steel, Mild Steel, Aluminium, Copper, Brass and other materials found in clinical practice, in particular synthetic floors, instruments and devices.

Exposure controls

• Skin contact: Low risk – may degrease skin leading to dryness if excessive contact.
• Eye contact: Low risk – may cause temporary discomfort.
• Inhalation: Low risk – avoid inhalation of fine mist spray.
• Inhalation (long term): Low risk – avoid inhalation of fine mist spray.
• Ingestion: Low risk – substantial ingestion will cause discomfort to mouth and digestive tissues.

Physical and chemical properties

• pH: 5.5 (approx)

Toxicological information

• Human Studies: 4 hour and 20 hours patch tests have shown minor skin reddening but no harmful effects.

Transport information

• No special conditions apply. Not dangerous.

Accidental release measures

• Environmental precautions: Product is biodegradable under OECD conditions operational 6/1995.
• Clean up method: Flush to drain with copious water or soak up onto inert material.

Ecological information

• No known adverse effects from normal use.
• The SteriGENE formula fully meets the criteria of the European Biocides Regulations which came into force in 2007.
• SteriGENE has not been tested on animals to secure its supporting data.

Because required results are generated with higher dilutions of SteriGENE , greater economies are effected at point of use. For example, an acceptable ‘kill’ rate for Parvo virus is widely accepted as 99.99% (log 4) in a thirty minute exposure. This corresponds to the test protocol used by the UK Animal Health Institute and to the protocol accepted world-wide under EPA conditions.

SteriGENE produces a 99.999+% (log 5+) kill rate in Parvo under the EPA protocol at a dilution of 1:100 (1 part disinfectant in 100 parts water).

Users of disinfectants in human health/laboratory and life science environments require maximum protection from the use of a disinfectant with proven independent microbiological test certification. Many disinfectants require strong dilutions for critical risk areas like Parvovirus or TB, yet are marketed for use at much weaker dilutions for “broad spectrum activity”, putting both the organisation and patients at risk of cross infection.

SteriGENE users can rely on one dilution (1:100) for broad spectrum activity (supported by independent testing) in high risk conditions against viruses, mycobacteria, fungi and bacterial organisms and another for economic general purpose disinfection (1:200) in intermediate risk areas.

Methodology	Organism	Log Reduction	Laboratory	Dilution	Clean/dirty conditions or low level soiling/high level soiling	Time
Mycobactericidal
P2, S1 EN 14348	Mycobacterium avium	>2.79	Abbott Analytical	1:100	dirty	30 mins
	Mycobacterium bovis	1.39	Abbott Analytical	1:100	dirty	30 mins
	Mycobacterium fortuitum	<7.14	Abbott Analytical	1:100	dirty	30 mins
	Mycobacterium terrae (TB)	>5.79	Abbott Analytical	1:100	dirty	30 mins
Virucidal
P2, S1 EN 14476	Canine parvovirus	5.67	Blutest	1:100	clean	30 mins
	Adenovirus T5	4.16	Blutest	1:100	clean	30 mins
	Feline Calicivirus	5.50	Blutest	1:100	clean	30 mins
U.S. EPA	Adenovirus T5	>5	ATS	1:100	5% FBS	30 mins
	Hepatitis B	>4.21	ATS	1:100	N/A	30 mins
	Human Immunodeficiency Virus T1	>4.5	ATS	1:100	5% FBS	30 mins
	Human Coronavirus	>4.75	ATS	1:100	1% FBS	30 mins
Fungicidal / Yeasticidal
P2, S2 EN 13697	Candida albicans	>3.4	MGS	1:100	dirty	5 mins
P2, S1 EN 13624	Candida albicans	>5.06	MGS	1:100	clean	5 mins
Bactericidal
P2,S2 EN 14561	Enterococcus hirae	5.24	MGS	1:100	clean	5 mins
P2, S1 EN 1656	Enterococcus hirae	>5.08	MGS	1:200	low level soiling	5 mins
	Staphylococcus aureus	>5.12	MGS	1:200	low level soiling	5 mins
	Campylobacter jejuni	>5.36	MGS	1:200	low level soiling	5 mins
	Stenotrophomonas maltophilia	>5.53	MGS	1:200	low level soiling	5 mins
	Methicillin-resistant Staphylococcus pseudimintermedius	>5.44	MGS	1:200	low level soiling	5 mins
	Proteus vulgaris	>5.16	MGS	1:200	low level soiling	5 mins
	Streptococcus equi	>5.34	MGS	1:200	low level soiling	5 mins
	Rhodococcus equi	5.40	MGS	1:100	low level soiling	5 mins
	Bordatella bronchiseptica	4.15	MGS	1:100	low level soiling	5 mins
P2, S1 EN 13727	Methicillin-resistant Staphylococcus aureus	>5.34	MGS	1:200	clean	5 mins
	Enterococcus hirae	>5.0	Eclipse	1:200	clean and dirty	5 mins
	Staphylococcus aureus	>5.0	Eclipse	1:200	clean and dirty	5 mins
	Pseudomonas aeruginosa	>5.0	Eclipse	1:200	clean and dirty	5 mins
P2, S1 EN 1276	Enterococcus hirae	>5.0	Eclipse	1:200	clean and dirty	5 mins
	Staphylococcus aureus	>5.0	Eclipse	1:200	clean and dirty	5 mins
	Pseudomonas aeruginosa	>5.0	Eclipse	1:200	clean and dirty	5 mins
	Escherichia coli	>5.0	Eclipse	1:200	clean and dirty	5 mins
P2, S1 EN 1650	Microsporum audouinii	>4.3	University of Huddersfield	1:100	clean	30 mins
	Trichophyton tonsurans	>4.1	University of Huddersfield	1:100	clean	60 mins